The late Sir Christopher Lee in The Curse of Frankenstein (who also played Count Dracula in the Hammer Films Dracula films, Fu Manchu in Hammer's Fu Manchu series, Lord Summerisle in The Wicker Man, Francisco Scaramanga in The Man with the Golden Gun, King Haggard in The Last Unicorn, Cushing Catheter in Gremlins 2: The New Batch, Saruman in Sir Peter Jackson's The Lord of the Rings and The Hobbit film trilogies, Count Dooku in the Star Wars prequel films, and The Jabberwock in Alice in Wonderland.
The late Bela Lugosi in Frankenstein Meets the Wolf Man (who also played Dracula in the Universal films).
Robert De Niro (who also played the young Vito Corleone in The Godfather Part II, Travis Bickle in Taxi Driver, Jake LaMotta in Raging Bull, David "Noodles" Aaronson in Once Upon a Time in America, Louis Cyphre in Angel Heart, Al Capone in The Untouchables, Jimmy Conway in Goodfellas, Dwight Hansen in This Boy's Life, Max Cady in Cape Fear, Neil McCauley in Heat, Gil Renard in The Fan, Ace Rothstein in Casino, Louis Gara in Jackie Brown, Fearless Leader in The Adventures of Rocky & Bullwinkle, Don Lino in Shark Tale, David Callaway in Hide & Seek and Senator John McLaughlin in Machete) played a version of the character in Mary Shelley's Frankenstein that is arguably the most faithful to the novel.
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The late Charles Stanton Ogle in the 1910 silent movie Frankenstein.
The character has been portrayed by several actors over the years, including: